synapsis shows twi types of response, some shows first greaz activity and the following responses are smaller and smaller, others shows first few response and later more response.

short term flexibility ob the brain is connected with extracellular calzim concentation which leads to coagulation of the nerve,
sometimes reversible,

long term flexbility of the brain is close to dynamic chemestry of benzenesdiscrets which interactions all have to be determinded,

but reducing the extracellular calciumconcentartion and the exactly right key for receptors is concern of many scientists round the world and the price for developing hydrogenebonding adaptive dynamic Polmers isnt calculable.